What SDF shows and how it is interpreted
Methods such as TUNEL, SCSA, and SCD are used. As a general guide: low <15%, borderline 15-25%, high >25-30% — always interpreted according to the specific method and laboratory.
Low DFI
A more favorable DNA integrity profile.
Borderline DFI
Requires clinical correlation and addressing modifiable risk factors.
High DFI
An increased risk of reduced reproductive performance, requiring a targeted strategy.
Clinical indications
It is useful in recurrent pregnancy loss, failed IVF/ICSI cycles, unexplained infertility, and when oxidative stress risk factors are present.
